CQUniversity Unit Profile
BMSC13002 Advanced Clinical Biochemistry
Advanced Clinical Biochemistry
All details in this unit profile for BMSC13002 have been officially approved by CQUniversity and represent a learning partnership between the University and you (our student).
The information will not be changed unless absolutely necessary and any change will be clearly indicated by an approved correction included in the profile.
Corrections

Unit Profile Correction added on 06-05-20

The end of term examination has now been changed to an alternate form of assessment. Please see your Moodle site for details of the assessment.

Unit Profile Correction added on 06-05-20

The Residential School for this unit has been postponed and you will need to complete it at a later date. Further details about the residential school will be made available on Moodle in due course.

General Information

Overview

On completion of this unit, you should be able to evaluate the evidence base for biochemical tests used in diagnosis and monitoring of diseases in the major organ systems of the body. Problem solving and decision making skills will be developed through use of authentic case studies. Skill development in instrument calibration, best practice measurement, interpretation of test results and test quality control monitoring will occur through practical exercises. You will be required to attend a residential school on Rockhampton campus in order to promote development of unit learning outcomes.

Details

Career Level: Undergraduate
Unit Level: Level 3
Credit Points: 6
Student Contribution Band: 8
Fraction of Full-Time Student Load: 0.125

Pre-requisites or Co-requisites

Pre-requisites: BMSC12010 Clinical Biochemistry or BMED19003 Clinical Biochemistry and BMSC11003 Introduction to Medical Science

Important note: Students enrolled in a subsequent unit who failed their pre-requisite unit, should drop the subsequent unit before the census date or within 10 working days of Fail grade notification. Students who do not drop the unit in this timeframe cannot later drop the unit without academic and financial liability. See details in the Assessment Policy and Procedure (Higher Education Coursework).

Offerings For Term 1 - 2020

Mixed Mode
Rockhampton

Attendance Requirements

All on-campus students are expected to attend scheduled classes – in some units, these classes are identified as a mandatory (pass/fail) component and attendance is compulsory. International students, on a student visa, must maintain a full time study load and meet both attendance and academic progress requirements in each study period (satisfactory attendance for International students is defined as maintaining at least an 80% attendance record).

Residential Schools

This unit has a Compulsory Residential School for distance mode students and the details are:
Click here to see your Residential School Timetable.

Class and Assessment Overview

Recommended Student Time Commitment

Each 6-credit Undergraduate unit at CQUniversity requires an overall time commitment of an average of 12.5 hours of study per week, making a total of 150 hours for the unit.

Class Timetable

Bundaberg, Cairns, Emerald, Gladstone, Mackay, Rockhampton, Townsville
Adelaide, Brisbane, Melbourne, Perth, Sydney

Assessment Overview

1. Written Assessment
Weighting: 20%
2. Practical and Written Assessment
Weighting: 30%
3. Examination
Weighting: 50%

Assessment Grading

This is a graded unit: your overall grade will be calculated from the marks or grades for each assessment task, based on the relative weightings shown in the table above. You must obtain an overall mark for the unit of at least 50%, or an overall grade of ‘pass’ in order to pass the unit. If any ‘pass/fail’ tasks are shown in the table above they must also be completed successfully (‘pass’ grade). You must also meet any minimum mark requirements specified for a particular assessment task, as detailed in the ‘assessment task’ section (note that in some instances, the minimum mark for a task may be greater than 50%). Consult the University’s Grades and Results Policy for more details of interim results and final grades.

Previous Student Feedback

Feedback, Recommendations and Responses

Every unit is reviewed for enhancement each year. At the most recent review, the following staff and student feedback items were identified and recommendations were made.

Feedback from Subject Review

Feedback

Revision of case study material for assessment

Recommendation

New case study material will be provided for the written assessment item in 2020 to provide enhanced variety in clinical laboratory scenarios.

Feedback from Subject Review

Feedback

Improve assessment feedback

Recommendation

Comprehensive and timely assessment feedback

Unit Learning Outcomes
On successful completion of this unit, you will be able to:
  1. Explain the various processes involved in biochemical method evaluation, interpretation and development.
  2. Explore the limitations of laboratory procedures, regulatory aspects including external quality assurance and accreditation bodies.
  3. Describe the rationale and clinical correlation of specialised biochemical tests used in the detection and monitoring of processes affecting the major organ systems.
  4. Demonstrate skills in the use of biochemical instrumentation, including specimen handling and test processing in automated systems and institution of appropriate corrective action as required in response to errors in automated instrumentation function.
  5. Evaluate biochemical clinical cases to derive a provisional diagnosis.
Alignment of Learning Outcomes, Assessment and Graduate Attributes
N/A Level
Introductory Level
Intermediate Level
Graduate Level
Professional Level
Advanced Level

Alignment of Assessment Tasks to Learning Outcomes

Assessment Tasks Learning Outcomes
1 2 3 4 5
1 - Written Assessment - 20%
2 - Practical and Written Assessment - 30%
3 - Examination - 50%

Alignment of Graduate Attributes to Learning Outcomes

Graduate Attributes Learning Outcomes
1 2 3 4 5
1 - Communication
2 - Problem Solving
3 - Critical Thinking
4 - Information Literacy
5 - Team Work
6 - Information Technology Competence
7 - Cross Cultural Competence
8 - Ethical practice
9 - Social Innovation

Alignment of Assessment Tasks to Graduate Attributes

Assessment Tasks Graduate Attributes
1 2 3 4 5 6 7 8 9
1 - Written Assessment - 20%
2 - Practical and Written Assessment - 30%
3 - Examination - 50%
Textbooks and Resources

Textbooks

Prescribed

Clinical Chemistry Principles, Techniques and Correlations 8th edn (2017)

Authors: Bishop, Fody, Schoeff
Wolters Kluwer
Philadelphia Philadelphia , PA , USA
ISBN: 9781496335586
Binding: Paperback

Additional Textbook Information

Copies can be purchased at the CQUni Bookshop here: http://bookshop.cqu.edu.au (search on the Unit code)

IT Resources

You will need access to the following IT resources:
  • CQUniversity Student Email
  • Internet
  • Unit Website (Moodle)
Referencing Style

All submissions for this unit must use the referencing styles below:

For further information, see the Assessment Tasks.

Teaching Contacts
Wayne Pederick Unit Coordinator
w.pederick@cqu.edu.au
Schedule
Week 1 Begin Date: 09 Mar 2020

Module/Topic

1. Introduction, Quality Control and External Quality Assessment

2. Analytical process, data interpretation and method evaluation

Chapter

Clinical Chemistry, Principles, Techniques and Correlations: 1 - 4

Clinical Chemistry, Principles, Techniques and Correlations: 3 & 4

Events and Submissions/Topic


Zoom tutorial - Introduction

Week 2 Begin Date: 16 Mar 2020

Module/Topic

1. Analytical techniques

2. Automation and POCT

Chapter

Clinical Chemistry, Principles, Techniques and Correlations: 5, 6, 8 & 9

Clinical Chemistry, Principles, Techniques and Correlations: 7 & 10

Events and Submissions/Topic

Zoom tutorial --  covering Week 1

Week 3 Begin Date: 23 Mar 2020

Module/Topic

Renal Function, electrolytes and fluid balance

Chapter

Clinical Chemistry, Principles, Techniques and Correlations: 12, 16 & 27

Events and Submissions/Topic

Zoom tutorial -- covering Week 2

Week 4 Begin Date: 30 Mar 2020

Module/Topic

Hepatic, pancreatic and GUT biochemistry, malabsorption etc.

Chapter

Clinical Chemistry, Principles, Techniques and Correlations: 25 & 28

Events and Submissions/Topic

Zoom tutorial -- covering Week 3

Week 5 Begin Date: 06 Apr 2020

Module/Topic

1.Cardio-respiratory system – cardiac damage, pH and blood gases

2. Endocrine system – thyroid, parathyroid, adrenal and pituitary; calcium metabolism

Chapter

Clinical Chemistry, Principles, Techniques and Correlations: 17 & 26

Clinical Chemistry, Principles, Techniques and Correlations: 20 - 24

Events and Submissions/Topic

Zoom tutorial -- covering Week 4 and discussion around Assessment #1 submission

Vacation Week Begin Date: 13 Apr 2020

Module/Topic

No lecture

Chapter

N/A

Events and Submissions/Topic

No Tutorial

Week 6 Begin Date: 20 Apr 2020

Module/Topic

Therapeutic Drug Monitoring and Toxicology

Chapter

Clinical Chemistry, Principles, Techniques and Correlations: 30 & 31

Events and Submissions/Topic

Zoom tutorial -- covering Week 5



Case study report Due: Week 6 Friday (24 Apr 2020) 11:45 pm AEST
Week 7 Begin Date: 27 Apr 2020

Module/Topic

1. Nutritional assessment – vitamins, minerals & trace metals

2. Extremes of age – neonatal, paediatric and geriatric biochemistry

Chapter

Clinical Chemistry, Principles, Techniques and Correlations: 18 & 33

Clinical Chemistry, Principles, Techniques and Correlations: 34 & 35

Events and Submissions/Topic

Zoom tutorial -- covering Week 6

Week 8 Begin Date: 04 May 2020

Module/Topic

1. Reproductive hormones

2. Carbohydrates & Lipids

Chapter

Clinical Chemistry, Principles, Techniques and Correlations: 20 & 22

Clinical Chemistry, Principles, Techniques and Correlations: 14 & 15

Events and Submissions/Topic

Zoom tutorial -- covering Week 7

Week 9 Begin Date: 11 May 2020

Module/Topic

1. Tumour markers

2.Body fluids other than blood – urine, CSF etc.

Chapter

Clinical Chemistry, Principles, Techniques and Correlations: 32

Clinical Chemistry, Principles, Techniques and Correlations: 29

Events and Submissions/Topic

Zoom tutorial -- covering Week 8

Week 10 Begin Date: 18 May 2020

Module/Topic

Residential School - 18th - 20th

Chapter

Laboratory Workbook


Events and Submissions/Topic

A tutorial will be run in the Residential School, an open Q&A session


Week 11 Begin Date: 25 May 2020

Module/Topic

Revision Lectures or presentation of ‘classic diseases’

Chapter

N/A

Events and Submissions/Topic

Zoom tutorial -- covering Week 9 and discussion around Assessment #2 submission.


Practical Assessment and Examination Due: Week 11 Monday (25 May 2020) 11:45 pm AEST
Week 12 Begin Date: 01 Jun 2020

Module/Topic

Exam Preparation

Chapter


Events and Submissions/Topic

Zoom tutorial -- Revision & Exam Preparation

Review/Exam Week Begin Date: 08 Jun 2020

Module/Topic


Chapter


Events and Submissions/Topic

Exam Week Begin Date: 15 Jun 2020

Module/Topic


Chapter


Events and Submissions/Topic


Term Specific Information

The Unit Coordinator for this Unit is Wayne Pederick who can be contacted by e-mail (w.pederick@cqu.edu.au) or via the Moodle forums.

Lectures will all be pre-recorded in smaller 'modules' and will be posted on the Moodle page.

There are weekly Tutorials that will be linked to Zoom and will also be recorded and posted to the Moodle page.

Assessment Tasks

1 Written Assessment

Assessment Title
Case study report

Task Description

You will be provided with a clinical case study on the Moodle site.

You will be provided with information regarding the clinical presentation, patient history and specific biochemical parameters (provided by an automated analyser) for this clinical case study. You are required to write a report (around 1,000 words) using a case study approach describing the pathophysiology, specific biochemical profile characteristics observed that led to the diagnosis, differential diagnosis, treatment options and any recommended further tests. Further details on the case, a template and an exemplar will be provided to you on the Moodle site to assist in preparation.


Assessment Due Date

Week 6 Friday (24 Apr 2020) 11:45 pm AEST


Return Date to Students

Week 8 Friday (8 May 2020)


Weighting
20%

Minimum mark or grade
50 %

Assessment Criteria

The assessment task is marked according to how well you have met the specific requirements and in accordance with the criteria outlined below:

Presentation: The report is presented in the provided template with clarity of purpose and coherence of expression (spelling, grammar, syntax) in a clear and organised manner.

Abstract: Provides a clear overview and overall summary of the case study.

Introduction: Provides necessary background information and pathophysiology of the case. Does not discuss the final diagnosis rather supports the intended diagnosis via arguments.

Materials and Methods: Briefly describes all the methods used to aid in diagnosis. Discusses further tests to be employed in order to confirm the diagnosis.

Results: All data presented clearly with reference ranges. Layout is clear with further tests and expected results discussed.

Discussion: Clear discussion of the results with supporting arguments and reasoning for arriving at the final diagnosis.

References: Correct referencing system used with appropriate in-text references


Referencing Style

Submission
Online

Learning Outcomes Assessed
  • Describe the rationale and clinical correlation of specialised biochemical tests used in the detection and monitoring of processes affecting the major organ systems.
  • Evaluate biochemical clinical cases to derive a provisional diagnosis.


Graduate Attributes
  • Communication
  • Problem Solving
  • Critical Thinking
  • Information Literacy

2 Practical and Written Assessment

Assessment Title
Practical Assessment and Examination

Task Description

You will be provided with a laboratory workbook on the Moodle site. This workbook will contain all the tasks that need to be completed during the residential school block. It will also contain a series of short questions and patient reports to be completed in relation to the authentic cases provided. Group experimental activities during the residential school will foster team work and provide hands-on experience of the biochemical techniques used in pathology laboratories. Completion of the workbook will evidence student engagement and understanding of the principles behind the Biochemical tests. Laboratory staff or demonstrators will assess your individual experimental capability during residential school to ensure your understanding of the learning outcomes. 

Important: On Day 3 of your residential school block you will have a final practical assessment. Further details regarding the practical assessment will be available on the Moodle page.


Assessment Due Date

Week 11 Monday (25 May 2020) 11:45 pm AEST

A scanned version of the laboratory workbook will be submitted on the Moodle page following the Residential School


Return Date to Students

Review/Exam Week Monday (8 Jun 2020)

Results of Practical Assessment will be posted on the Moodle page.


Weighting
30%

Minimum mark or grade
50%

Assessment Criteria

  • Residential school and Workbook component: Each section will have respective assigned marks as indicated on the provided workbook. A total mark obtained for the workbook and associated tasks would then represent to 20% of your final grade. The laboratory staff will provide immediate verbal feedback to you on the practical hands-on aspect of this assessment item. The laboratory workbook template will contain the weighting of marks associated with the tasks and subsequent questions/reports to be completed
  • Practical assessment component: The practical assessment conducted on Day 3 of the Residential School is worth 10% of your final grade. Further information on the practical assessment will be available on the Moodle page.
  • Total for practical assessment: 20 + 10 = 30%


Referencing Style

Submission
Online

Learning Outcomes Assessed
  • Explore the limitations of laboratory procedures, regulatory aspects including external quality assurance and accreditation bodies.
  • Demonstrate skills in the use of biochemical instrumentation, including specimen handling and test processing in automated systems and institution of appropriate corrective action as required in response to errors in automated instrumentation function.
  • Evaluate biochemical clinical cases to derive a provisional diagnosis.


Graduate Attributes
  • Communication
  • Problem Solving
  • Critical Thinking
  • Information Literacy
  • Team Work

Examination

Outline
Complete an examination

Date
During the University examination period

Weighting
50%

Length
180 minutes

Minimum mark or grade
Students must receive at least 50% of the final examination mark to pass subject

Details
Dictionary - non-electronic, concise, direct translation only (dictionary must not contain any notes or comments).
Closed Book
Academic Integrity Statement

As a CQUniversity student you are expected to act honestly in all aspects of your academic work.

Any assessable work undertaken or submitted for review or assessment must be your own work. Assessable work is any type of work you do to meet the assessment requirements in the unit, including draft work submitted for review and feedback and final work to be assessed.

When you use the ideas, words or data of others in your assessment, you must thoroughly and clearly acknowledge the source of this information by using the correct referencing style for your unit. Using others’ work without proper acknowledgement may be considered a form of intellectual dishonesty.

Participating honestly, respectfully, responsibly, and fairly in your university study ensures the CQUniversity qualification you earn will be valued as a true indication of your individual academic achievement and will continue to receive the respect and recognition it deserves.

As a student, you are responsible for reading and following CQUniversity’s policies, including the Student Academic Integrity Policy and Procedure. This policy sets out CQUniversity’s expectations of you to act with integrity, examples of academic integrity breaches to avoid, the processes used to address alleged breaches of academic integrity, and potential penalties.

What is a breach of academic integrity?

A breach of academic integrity includes but is not limited to plagiarism, self-plagiarism, collusion, cheating, contract cheating, and academic misconduct. The Student Academic Integrity Policy and Procedure defines what these terms mean and gives examples.

Why is academic integrity important?

A breach of academic integrity may result in one or more penalties, including suspension or even expulsion from the University. It can also have negative implications for student visas and future enrolment at CQUniversity or elsewhere. Students who engage in contract cheating also risk being blackmailed by contract cheating services.

Where can I get assistance?

For academic advice and guidance, the Academic Learning Centre (ALC) can support you in becoming confident in completing assessments with integrity and of high standard.

What can you do to act with integrity?