LMED29001 - Genomic Pathology 1

Showing: 2026 HE Term 1
General Information

Unit Synopsis

Molecular and cellular pathology involves the study of disease processes at the molecular level and allows diagnosis of disease through the detection of genetic mutations, dysregulated gene expression and non functional or cytotoxic proteins. In this unit, you will learn about the role of cellular genetic material and associated genetic rearrangements and mutations. You will explore the application of molecular techniques, such as polymerase chain reaction and next generation sequencing, and their revolutionary impact on diagnostic testing. The residential school may be scheduled outside of the term of offering of the unit.

Details

Level Postgraduate
Unit Level 9
Credit Points 6
Student Contribution Band SCA Band 2
Fraction of Full-Time Student Load 0.125
Pre-requisites or Co-requisites

Prerequisites:

Enrolment in Master of Laboratory Medicine.

Important note: Students enrolled in a subsequent unit who failed their pre-requisite unit, should drop the subsequent unit before the census date or within 10 working days of Fail grade notification. Students who do not drop the unit in this timeframe cannot later drop the unit without academic and financial liability. See details in the Assessment Policy and Procedure (Higher Education Coursework).

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Residential School Compulsory Residential School
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Unit Availabilities from Term 1 - 2026

Term 2 - 2026 Profile
Melbourne Mixed Mode Rockhampton Sydney

Attendance Requirements

All on-campus students are expected to attend scheduled classes - in some units, these classes are identified as a mandatory (pass/fail) component and attendance is compulsory. International students, on a student visa, must maintain a full time study load and meet both attendance and academic progress requirements in each study period (satisfactory attendance for International students is defined as maintaining at least an 80% attendance record).

Assessment Overview

Recommended Student Time Commitment

Each 6-credit Postgraduate unit at CQUniversity requires an overall time commitment of an average of 12.5 hours of study per week, making a total of 150 hours for the unit.

Assessment Tasks

Assessment Task Weighting
1. Written Assessment 20%
2. Written Assessment 30%
3. Laboratory/Practical 0%
4. Examination 50%

This is a graded unit: your overall grade will be calculated from the marks or grades for each assessment task, based on the relative weightings shown in the table above. You must obtain an overall mark for the unit of at least 50%, or an overall grade of ‘pass’ in order to pass the unit. If any ‘pass/fail’ tasks are shown in the table above they must also be completed successfully (‘pass’ grade). You must also meet any minimum mark requirements specified for a particular assessment task, as detailed in the ‘assessment task’ section (note that in some instances, the minimum mark for a task may be greater than 50%).

Consult the University's Grades and Results Policy for more details of interim results and final grades

Past Exams

Previous Feedback

Term 2 - 2025 : The overall satisfaction for students in the last offering of this course was 90.00% (`Agree` and `Strongly Agree` responses), based on a 18.02% response rate.

Feedback, Recommendations and Responses

Every unit is reviewed for enhancement each year. At the most recent review, the following staff and student feedback items were identified and recommendations were made.

Source: SUTE
Feedback:
Students appreciate the short, bite-sized lecture recordings.

Recommendation:
Consider continuing this method of recording and delivering lectures.

Action Taken:
Bite-sized lecture recordings continued from weeks 1 - week 11 lectures.
Source: SUTE
Feedback:
Students like the case studies associated with each topics

Recommendation:
Consider continuing and expanding the use of case studies in the tutorial sessions.

Action Taken:
Case studies were included for each topic and week
Source: SUTE
Feedback:
Some students like the Kahoot Quizzes to be included in the tutorial sessions.

Recommendation:
Consider re-introducing the Kahoot quizzes, and to be run towards the end of the tutorial sessions

Action Taken:
Due to time constraints, Kahoot quizzes were not used. Instead, for each tutorial topic, more than 20 short-answer questions were discussed in detail, with model answers subsequently made available on the subject Moodle site.
Source: Self-reflection
Feedback:
Residential school experiments

Recommendation:
Consider incorporating additional experiments during the residential school, as there is capacity to include more practical work.

Action Taken:
In Progress
Source: SUTE and self-reflection
Feedback:
Tutorial format has been engaging

Recommendation:
Retain the current tutorial format, with questions provided one week in advance and reviewed during face-to-face tutorial sessions.

Action Taken:
In Progress
Source: Self-reflection
Feedback:
The topic Molecular Basis of Prostate, Colorectal, and Breast Cancer requires an additional lecture/tutorial session, as the existing allocation is insufficient to adequately cover the breadth and depth of the content.

Recommendation:
Consider adding an additional lecture/tutorial session to adequately cover this topic. This could be achieved by replacing the existing blood lecture topic with this content (as the blood related topic is also covered in LMED28002)

Action Taken:
In Progress
Unit Learning Outcomes

On successful completion of this unit, you will be able to:

  1. Critically discuss how gene mutations or rearrangements underpin the molecular aetiology of particular diseases
  2. Evaluate the role of epigenetic modifications of the genome in disease pathogenesis
  3. Explain the process of identifying genetic modifications and their clinical significance
  4. Demonstrate skills in the use of genetic techniques in molecular pathology, including genetic amplification
  5. Explain the use of molecular pathology in disease diagnosis, prevention and treatment, including the development of personalised medicines.
Alignment of Assessment Tasks to Learning Outcomes
Assessment Tasks Learning Outcomes
1 2 3 4 5
1 - Written Assessment
2 - Written Assessment
3 - Laboratory/Practical
4 - Examination
Alignment of Graduate Attributes to Learning Outcomes
Professional Level
Advanced Level
Graduate Attributes Learning Outcomes
1 2 3 4 5
1 - Knowledge
2 - Communication
3 - Cognitive, technical and creative skills
Alignment of Assessment Tasks to Graduate Attributes
Professional Level
Advanced Level
Assessment Tasks Graduate Attributes
1 2 3 4 5 6 7 8 8